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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 11.21
Human Site: S190 Identified Species: 15.42
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S190 R A K E N T F S K A D A E Y K
Chimpanzee Pan troglodytes XP_519198 1283 142803 S190 R A K E N T F S K A D A E Y K
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S190 Q T K E N T F S K A D A E Y K
Dog Lupus familis XP_532459 1267 140567 L176 L E T D T K L L I L P K T R Q
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 P190 Q A K E S T F P K E G D A H G
Rat Rattus norvegicus P46462 806 89330
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 G171 Q I R I V F P G A V F P I W V
Chicken Gallus gallus XP_418655 1290 143066 S193 E N I I D M P S T E S D I L L
Frog Xenopus laevis P23787 805 89193
Zebra Danio Brachydanio rerio Q7ZU99 806 89405
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841
Honey Bee Apis mellifera XP_397107 1069 120490 V92 P I L I K I N V A P L T V N D
Nematode Worm Caenorhab. elegans P54812 810 89622
Sea Urchin Strong. purpuratus XP_797089 1508 166130 E266 N I P S M P W E V D P V D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 H66 V H L G W D G H D S G S S E N
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 S258 K T K R S S A S G Q Q Q G R K
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 100 86.6 0 N.A. 40 0 N.A. 0 6.6 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 100 93.3 13.3 N.A. 60 0 N.A. 20 13.3 0 0 N.A. 0 0 0 20
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 0 0 20
P-Site Similarity: N.A. N.A. N.A. 0 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 18 0 0 0 0 6 0 12 18 0 18 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 6 6 0 0 6 6 18 12 6 0 6 % D
% Glu: 6 6 0 24 0 0 0 6 0 12 0 0 18 6 6 % E
% Phe: 0 0 0 0 0 6 24 0 0 0 6 0 0 0 0 % F
% Gly: 0 0 0 6 0 0 6 6 6 0 12 0 6 0 6 % G
% His: 0 6 0 0 0 0 0 6 0 0 0 0 0 6 0 % H
% Ile: 0 18 6 18 0 6 0 0 6 0 0 0 12 0 0 % I
% Lys: 6 0 30 0 6 6 0 0 24 0 0 6 0 0 24 % K
% Leu: 6 0 12 0 0 0 6 6 0 6 6 0 0 6 6 % L
% Met: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 6 0 0 18 0 6 0 0 0 0 0 0 6 6 % N
% Pro: 6 0 6 0 0 6 12 6 0 6 12 6 0 0 0 % P
% Gln: 18 0 0 0 0 0 0 0 0 6 6 6 0 0 6 % Q
% Arg: 12 0 6 6 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 0 0 6 12 6 0 30 0 6 6 6 6 0 0 % S
% Thr: 0 12 6 0 6 24 0 0 6 0 0 6 6 0 0 % T
% Val: 6 0 0 0 6 0 0 6 6 6 0 6 6 6 6 % V
% Trp: 0 0 0 0 6 0 6 0 0 0 0 0 0 6 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _